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HUBUNGAN RIWAYAT INFEKSI COVID-19 TERHADAP KADAR ANTIBODI S1RBD IgG PADA CIVITAS AKADEMIKA POLTEKKES KEMENKES BANJARMASIN
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ABSTRAK
HUBUNGAN RIWAYAT INFEKSI COVID-19 TERHADAP ANTIBODI
S1RBD IgG PADA CIVITAS AKADEMIKA POLTEKKES KEMENKES
BANJARMASIN
Peneliti : Farah Shoffa Shafira
Pembimbing : Wahdah Norsiah, Tini Elyn Herlina
Wabah pandemi COVID-19 memiliki prevalensi yang tinggi di berbagai
negara, salah satunya Indonesia. Berdasarkan data Kemenkes RI, hingga Mei
2023 tercatat lebih dari 6 Juta orang di Indonesia terkonfirmasi COVID-19.
Tujuan dari penelitian ini adalah untuk mengetahui hubungan riwayat infeksi
COVID-19 terhadap kadar Antibodi S1RBD IgG. Penelitian dilakukan di
Laboratorium Imunoserologi jurusan Analis Kesehatan Poltekkes Kemenkes
Banjarmasin pada tanggal 29 Desember 2022 – 27 Maret 2023. Penelitian
menggunakan metode cross sectional study dengan populasi seluruh Civitas
Akademika yang berada di lingkungan Poltekkes Kemenkes Banjarmasin lalu
sampel diambil menggunakan teknik purposive sampling dan diambil sebanyak
30 sampel. Hasil penelitian menunjukkan penurunan rata-rata kadar antibodi
berdasarkan waktu infeksi. Untuk waktu 2-10 bulan pasca infeksi sebesar 281,271
IU/mL, 10-18 bulan sebesar 255,801 IU/mL, dan 18-26 bulan sebesar 178,567
IU/mL. Selain itu, terjadi peningkatan rata-rata kadar antibodi berdasar banyaknya
pengulangan infeksi COVID-19. Untuk 1x sebesar 225,824 IU/mL, sedangkan
untuk 2x sebesar 251,269 IU/mL. Saran Bagi Civitas Akademika di lingkungan
Pendidikan Kesehatan terutama yang memiliki Respon Imun COVID-19 Rendah
untuk melakukan vaksinasi booster sebagai proteksi diri dalam mengurangi risiko
penularan COVID-19. Bagi peneliti selanjutnya, dapat melakukan penelitian yang
serupa pada subjek penelitian yang berbeda seperti pengidap riwayat penyakit
tertentu atau subjek-subjek penelitian lain yang terkait.
Kata Kunci : COVID-19, Antibodi, S1RBD, IgG, Civitas Akademika
ix
ABSTRACT
THE RELATION OF COVID-19 INFECTION HISTORY TO S1RBD IgG
ANTIBODY LEVELS IN CIVITAS ACADEMICA OF POLTEKKES
KEMENKES BANJARMASIN
Author : Farah Shoffa Shafira
Advisor : Wahdah Norsiah, Tini Elyn Herlina
The COVID-19 pandemic outbreak has a high prevalence in various
countries, one of which is Indonesia. Based on data from the Indonesia Ministry
of Health, until May 2023 there were more than 6 million people in Indonesia
confirmed with COVID-19. The purpose of this study was to determine the
relation of COVID-19 infection history to S1RBD IgG antibody levels. This study
was conducted at the Immunoserology Laboratory, Department of Health Analyst,
Poltekkes Kemenkes Banjarmasin, on 29 December 2022 – 27 March 2023. This
study used a cross-sectional study method with population of all civitas academica
who were in Poltekkes Kemenkes Banjarmasin then 30 samples were taken using
a purposive sampling technique. The results showed a decrease in the average
antibody level over time. For 2-10 months post-infection was 281.271 IU/mL, 10-
18 months post-infection was 255.801 IU/mL, and 18-26 months post-infection
was 178.567 IU/mL. In addition, there was an increase in the average antibody
level based on the number of repetitions of COVID-19 infection. For 1 time was
225.824 IU/mL, and for 2 times was 251.269 IU/mL. Suggestions for the Civitas
Academica in the Health Education environment, especially those with a Low
COVID-19 Immune Response to carry out booster vaccinations as self-protection
in reducing the risk of transmission of COVID-19. For future researchers, they
can conduct similar research on different research subjects such as people with a
history of certain diseases or other related research subjects.
Keywords : COVID-19, Antibody, S1RBD, IgG, Civitas Academica
Detail Information
| Item Type | |
|---|---|
| Penulis |
Farah Shoffa Shafira - Personal Name
Wahdah Norsiah, M.Si - Personal Name Tini Elyn Herlina - Personal Name |
| Student ID | |
| Dosen Pembimbing | |
| Penguji | |
| Kode Prodi PDDIKTI | |
| Edisi | |
| Departement | |
| Kontributor | |
| Bahasa |
Indonesia
|
| Penerbit | Jurusan Analis Kesehatan : Banjarbaru., 2023 |
| Edisi | |
| Subyek | |
| No Panggil |
013 SKP/ TLM 2023
|
| Copyright | |
| Doi |