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Perbedaan Kadar D-dimer Pada Ibu Hamil Tanpa Dan Disertai COVID-19 Di RSUD dr. Doris Sylvanus
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ABSTRAK
Perbedaan Kadar D-dimer Pada Ibu Hamil Tanpa Dan Disertai COVID-19
Di RSUD dr. Doris Sylvanus
Peneliti: Gina Tania
Pembimbing: Ahmad Muhlisin, Tini Elyn Herlina
ABSTRAK
Pada ibu hamil, perubahan imunitas mengakibatkan penurunan jumlah limfosit
sehingga meningkatkan kerentanan ibu hamil terhadap infeksi virus selama
kehamilan. Perubahan fisiologis mengakibatkan peningkatan kadar D-dimer seiring
peningkatan usia kehamilan. D-dimer adalah produk akhir degenerasi cross-linked
fibrin oleh aktivitas kerja plasmin dalam sistem fibrinolitik yang digunakan untuk
mendeteksi adanya trombosis. Sejumlah pasien COVID -19 mengalami disfungsi
koagulasi dan D-dimer meningkat secara substansial. Oleh karena itu wanita
hamil dengan COVID-19 memiliki faktor risiko lebih besar untuk terjadinya
peningkatan D-dimer. Penelitian ini bertujuan untuk mengetahui perbedaan kadar
D-dimer pada ibu hamil tanpa dan disertai COVID -19 di RSUD dr. Doris Sylvanus
periode Januari Tahun 2022 sampai Agustus Tahun 2023. Penelitian ini
menggunakan metode survei analitik dengan desain studi kasus komparatif dan
teknik pengambilan sampel menggunakan total sampling. Subjek penelitian ini
adalah 19 ibu hamil trimester ketiga dengan hasil tes cepat antigen virus COVID-
19 negatif dan 19 ibu hamil dengan hasil tes cepat antigen dan tes RT-PCR virus
COVID-19 positif. Analisis data menggunakan program komputer dengan Uji T
Independent, hasil uji menunjukkan Sig. (2-tailed) 0,043 (<0,05) artinya secara
statistik rata-rata kadar D-dimer pada ibu hamil tanpa dan disertai COVID-19
memiliki perbedaan bermakna. Dengan demikian dapat disimpulkan terdapat
perbedaan kadar D-dimer antara ibu hamil tanpa dan disertai COVID-19 di RSUD
Doris Sylvanus. Dimasa yang akan datang agar dilakukan penelitian lebih lanjut
terkait kadar D-dimer pada ibu hamil tanpa atau disertai komplikasi.
Kata kunci: Ibu hamil, D-dimer, COVID-19
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ABSTRACT
Differences in D-Dimer Levels in Pregnant Women Without and
Accompanied by COVID-19 at RSUD dr. Doris Sylvanus
Researcher: Gina Tania
Supervisor: Ahmad Muhlisin, Tini Elyn Herlina
ABSTRACT
In pregnant women, changes in immunity result in decreased lymphocyte counts,
increasing the susceptibility of pregnant women to viral infections during
pregnancy. Physiological changes result in increased D-dimer levels as gestational
age increases. D-dimer is the end product of degeneration of cross-linked fibrin by
the action of plasmin in the fibrinolytic system used to detect thrombosis. A number
of COVID-19 patients have coagulation dysfunction and D-dimer is substantially
elevated. Therefore, pregnant women with COVID19 have a greater risk factor for
an increase in D-dimer. This study aims to determine the difference in D-dimer
levels in pregnant women without and with COVID -19 at RSUD dr. Doris
Sylvanus for the period January 2022 to August 2023. This study used an analytic
survey method with a comparative case study design and the sampling technique
used total sampling. The subjects of this study were 19 third trimester pregnant
women with negative COVID-19 virus antigen rapid test results and 19 pregnant
women with positive COVID-19 virus antigen rapid test and RT-PCR test results.
Data analysis using a computer program with the Independent T Test, the test
results showed Sig. (2-tailed) 0.043 (<0.05) means that statistically the average D-
dimer level in pregnant women women without and with COVID-19 has a
significant difference. Thus it can be concluded that there is a significant difference
in d-dimer levels between pregnant women without and with COVID-19 at Doris
Sylvanus Hospital. In the future, further research should be carried out related to
D-dimer levels in pregnant women without or with complications.
Keywords: Pregnant women, D-dimer, COVID-19
Detail Information
| Item Type | |
|---|---|
| Penulis | |
| Student ID | |
| Dosen Pembimbing | |
| Penguji | |
| Kode Prodi PDDIKTI | |
| Edisi | |
| Departement | |
| Kontributor | |
| Bahasa |
Indonesia
|
| Penerbit | Jurusan Analis Kesehatan : Banjarbaru., 2023 |
| Edisi | |
| Subyek | |
| No Panggil |
SKP AJ 011J TLM/ 2023
|
| Copyright | |
| Doi |