Muslih - Pengarang
Jujuk Anton Cahyono, S.Si.,M.Sc - Dosen Pembimbing 1
Neni Oktiyani, S.Pd, M.Sc - Dosen Pembimbing 2

ABSTRAK

HUBUNGAN KADAR HBA1C DENGAN KADAR KOLESTEROL TOTAL

PADA PASIEN DIABETES MELITUS
DI LABORATORIUM KLINIK PRODIA MARTAPURA

Peneliti : Muslih

Pembimbing : Jujuk Anton Cahyono, Neni Oktiyani

Diabetes melitus (DM) merupakan penyakit dimana kadar glukosa darah
penderita melebihi normal disertai resistensi insulin atau tidak memproduksi
insulin. Resistensi insulin akan meningkatkan metabolisme lemak atau profil
lipid yang akan memberi efek salah satunya enzim lipase yang sensitive
terhadap hormon. Hormon didalam sel lemak akan teraktivasi, sehingga kadar
kolesterol akan meningkat. Pemeriksaan HbA1c selama ini lebih dikenal
untuk monitoring kontrol glikemik jangka panjang, penyesuaian terapi,
menilai kualitas perawatan diabetes mellitus, memprediksi risiko komplikasi
dan manfaat HbA1c sekarang ini dapat digunakan untuk skrining maupun
diagnosis diabetes. Tujuan penelitian ini untuk mengetahui hubungan kadar
HbA1c dengan kolesterol total pada pasien Diabetes melitus di Laboratorium
Klinik Prodia Martapura. Penelitian ini menggunakan metode Survey
Analitik dengan desain cross sectional. Sampel pada penelitian ini berjumlah
100 orang yang melakukan pemeriksaan di Laboratorium Klinik Prodia
Martapura. Hasil penelitian ini didapatkan nilai rerata kadar HbA1c 7.892%,
kadar kolesterol 228.47 mg/dL. Berdasarkan hasil uji statistik didapatkan
adanya korelasi yang bermakna antara kadar HbA1c dan kadar kolesterol total
pada pasien Diabetes melitus di Laboratorium Klinik Prodia Martapura.
Saran bagi peneliti selanjutnya diharapkan agar melakukan pemeriksaann
profil lipid (HDL, LDL dan Trigliserida) pada pasien Diabetes melitus
terhadap pasien obesitas dan untuk pasien Laboratorium Klinik Prodia
Martapura diharapkan lebih menjaga pola makan, gaya hidup yang lebih sehat
dan patuh dalam mengkonsumsi obat dari dokter.

Kata Kunci : Diabetes melitus, Kadar HbA1c, Kadar Kolesterol

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ABSTRACT

RELATIONSHIP OF HBA1C LEVELS WITH TOTAL CHOLESTEROL LEVELS

IN DIABETES MELLITUS PATIENTS
AT THE PRODIA MARTAPURA CLINIC LABORATORY

Author : Muslih

Advisors : Jujuk Anton Cahyono, Neni Oktiyani

Diabetes mellitus (DM) is a disease in which the patient's blood glucose level
exceeds normal accompanied by insulin resistance or not producing insulin.
Insulin resistance will increase fat metabolism or lipid profile which will have
an effect, one of which is the lipase enzyme which is sensitive to hormones.
Hormones in fat cells will be activated, so cholesterol levels will increase.
HbA1c examination has been better known for monitoring long-term
glycemic control, adjusting therapy, assessing the quality of diabetes mellitus
care, predicting the risk of complications and benefits. HbA1c can now be
used for screening and diagnosing diabetes. The aim of this study was to
determine the relationship between HbA1c levels and total cholesterol in
Diabetes mellitus patients at the Prodia Martapura Clinical Laboratory. This
research uses the Analytical Survey method with a cross sectional design. The
sample in this study consisted of 100 people who carried out examinations at
the Prodia Martapura Clinical Laboratory. The results of this study showed
that the mean HbA1c level was 7.892%, cholesterol level was 228.47 mg/dL.
Based on the results of statistical tests, it was found that there was a
significant correlation between HbA1c levels and total cholesterol levels in
Diabetes mellitus patients at the Prodia Martapura Clinical Laboratory.
Suggestions for future researchers are to carry out lipid profile checks (HDL,
LDL and Triglycerides) in Diabetes mellitus patients, obese patients and for
Prodia Martapura Clinical Laboratory patients, they are expected to
maintain a healthier diet, lifestyle and comply with taking medication from
doctors.

Keywords: Diabetes mellitus, HbA1c levels, cholesterol levels

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