CD-ROM
PENGARUH WAKTU VAKSINASI BOOSTER COVID-19 TERHADAP KADAR ANTIBODI S1RBD IgG PADA SIVITAS AKADEMIKA JURUSAN ANALIS KESEHATAN POLTEKKES KEMENKES BANJARMASIN
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ABSTRAK
PENGARUH WAKTU VAKSINASI BOOSTER COVID-19 TERHADAP
KADAR ANTIBODI S1RBD IgG PADA SIVITAS AKADEMIKA
JURUSAN ANALIS KESEHATAN POLTEKKES KEMENKES
BANJARMASIN
Peneliti: Muhammad Rizki
Pembimbing: Haitami, Tini Elyn Herlina
Dalam rangka menanggulangi pandemi COVID-19, Pemerintah Republik
Indonesia sudah berupaya melalui Keputusan Presiden Nomor 50 Tahun 2021
tentang pengadaan vaksin dan pelaksanaan vaksinasi COVID-19. Upaya vaksinasi
terus dilakukan kepada masyarakat salah satunya adalah sivitas akademika
Jurusan Analis Kesehatan Poltekkes Kemenkes Banjarmasin yang sebagian besar
sudah menerima vaksin COVID-19, termasuk dosis booster. Dalam penelitian
Uysal et al. pada tahun 2021 mereka menguji respons antibodi 4 minggu setelah
dosis vaksin kedua dan 3 bulan setelah dosis vaksin kedua. Hasilnya adalah terjadi
penurunan nilai median titer antibodi dari 92,3 U/ml menjadi 54,0 U/ml. Tujuan
penelitian ini untuk mengetahui pengaruh waktu vaksinasi booster COVID-19
terhadap kadar antibodi S1RBD IgG pada sivitas akademika Jurusan Analis
Kesehatan Poltekkes Kemenkes Banjarmasin. Metode penelitian yang digunakan
survei analitik dengan rancangan cross sectional study. Penelitian ini mengambil
sampel dari 30 orang sivitas akademika Poltekkes Kemenkes Banjarmasin yang
telah menerima vaksin booster. Sampel dibagi menjadi 3 kelompok, yaitu
kelompok setelah vaksinasi booster dalam kisaran waktu 0–3 bulan, 3–6 bulan,
dan 6–9 bulan. Hasil rata-rata kadar antibodi S1RBD IgG pada ketiga kelompok
mengalami penurunan berturut-turut 291,589 IU/mL, 247,190 IU/mL, dan
176,860 IU/mL. Kesimpulan penelitian ini adalah terdapat pengaruh yang
signifikan antara waktu vaksinasi booster COVID-19 terhadap kadar antibodi
S1RBD IgG. Peneliti selanjutnya disarankan untuk memperluas jangkauan waktu
vaksinasi booster COVID-19 yang kemungkinan dapat menunjukkan hasil kadar
antibodi yang lebih rendah.
Kata kunci: waktu, vaksinasi, booster, antibodi
ix
ABSTRACT
THE EFFECT OF TIME OF COVID-19 BOOSTER VACCINATION ON
S1RBD IgG ANTIBODY LEVELS IN THE ACADEMIC COMMUNITY OF
HEALTH ANALYST DEPARTMENT, POLTEKKES KEMENKES
BANJARMASIN
Researcher: Muhammad Rizki
Advisor: Haitami, Tini Elyn Herlina
In order to tackle the COVID-19 pandemic, the Government of the
Republic of Indonesia has made efforts through Presidential Decree Number 50 of
2021 concerning the procurement of vaccines and the implementation of COVID-
19 vaccinations. Vaccination efforts are still being carried out to the community,
one of which is the academic community of the Health Analyst Department,
Poltekkes Kemenkes Banjarmasin, most of whom have received the COVID-19
vaccine, including booster doses. In a study by Uysal et al. in 2021 they tested for
antibody response 4 weeks after the second vaccine dose and 3 months after the
second vaccine dose. The result was a decrease in the median antibody titer from
92.3 U/ml to 54.0 U/ml. The purpose of this study was to determine the effect of
the timing of the COVID-19 booster vaccination on S1RBD IgG antibody levels
in the academic community of Poltekkes Kemenkes Banjarmasin. The research
method used was an analytic survey with a cross sectional study design. This
study took samples from 30 academics from the Health Analyst Department,
Poltekkes Kemenkes Banjarmasin who had received a booster vaccine. The
sample was divided into 3 groups, namely the group after booster vaccination in
the range of 0–3 months, 3–6 months, and 6–9 months. The average S1RBD IgG
antibody levels in the three groups decreased respectively to 291,589 IU/mL,
247,190 IU/mL, and 176,860 IU/mL. The conclusion of this study is that there is a
significant effect between the timing of the COVID-19 booster vaccination on
S1RBD IgG antibody levels. Future researchers are advised to expand the time
range of the COVID-19 booster vaccination which may result in lower antibody
levels.
Keywords: time, vaccination, booster, antibody
Detail Information
| Item Type | |
|---|---|
| Penulis | |
| Student ID | |
| Dosen Pembimbing | |
| Penguji | |
| Kode Prodi PDDIKTI | |
| Edisi | |
| Departement | |
| Kontributor | |
| Bahasa |
Indonesia
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| Penerbit | Jurusan Analis Kesehatan : Banjarbaru., 2023 |
| Edisi | |
| Subyek | |
| No Panggil |
032 SKP/TLM 2023
|
| Copyright | |
| Doi |