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Perbandingan Hasil Pemeriksaan Mycobacterium tuberculosis Pada Sampel Sputum Segera Dan Tunda 12 Jam Dengan Metode Tes Cepat Molekuler (TCM)
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ABSTRAK
Perbandingan Hasil Pemeriksaan Mycobacterium tuberculosis Pada
Sampel Sputum Segera Dan Tunda 12 Jam Dengan Metode Tes Cepat
Molekuler (TCM)
Peneliti : Yola Febrianti
Pembimbing : Ratih Dewi Dwiyanti, Wahdah Norsiah
Tuberkulosis merupakan masalah kesehatan masyarakat yang masih
menjadi tantangan secara global dan nasional. Penyakit tuberkulosis disebabkan
oleh bakteri Mycobacterium tuberculosis. Untuk menegakkan diagnosa penyakit
TB dengan pemeriksaan laboratorium menggunakan metode Tes Cepat
Molekuler (TCM) karena metode ini lebih sensitif dan akurat dibandingkan
metode konvensional, dan sekaligus dapat mendeteksi sensitivitas Rifampisin.
Tujuan penelitian ini untuk mengetahui perbedaan hasil pemeriksaan TB pada
metode TCM menggunakan alat GeneXpert terhadap penundaan penanganan
sputum pada tersangka tuberkulosis di RSUD Pangeran Jaya Sumitra Kotabaru.
Metode penelitian ini adalah Survey Analitik dengan menggunakan rancangan
penelitian Cross Sectional Studies dengan membandingkan hasil pemeriksaan
Mycobacterium tuberculosis pada sampel sputum yang diperiksa segera dengan
sampel sputum yang ditunda selama 12 jam pada suhu ruang dan selanjutnya data
di analisis secara statistik menggunakan uji Wilcoxon. Hasil penelitian
menunjukkan bahwa dari total 46 sampel sputum yang dilakukan penelitian
didapatkan hasil pemeriksaan sputum segera yaitu MTB Not Detected 33 sampel,
MTB Detected Very Low 3 sampel, MTB Detected Low 6 sampel, dan MTB
Detected Medium 4 sampel. Untuk sampel yang ditunda 12 jam pada suhu ruang
didapatkan hasil MTB Not Detected 33 sampel, MTB Detected Very Low 3
sampel, MTB Detected Low 6 sampel, dan MTB Detected Medium 4 sampel.
Kesimpulan penelitian ini yaitu tidak terdapat perbedaan hasil pemeriksaan
Mycobacterium tuberculosis pada sampel sputum segera dengan yang ditunda 12
jam pada suhu ruang. Saran penelitian ini adalah diperlukan penelitian lebih
lanjut mengenai variabel lain yang dapat mempengaruhi hasil pemeriksaan TB
metode TCM seperti variasi waktu penundaan, suhu, dan lain sebagainya.
Kata Kunci: Mycobacterium tuberculosis, Tes Cepat Molekuler, Sputum
viii
ABSTRACT
Comparison of Mycobacterium tuberculosis Test Result
on Sputum Samples Between Immediate and 12 Hours
Postponed Samples With The Molecular Rapid Test
(TCM) Method
Author : Yola Febrianti
Advisor : Ratih Dewi Dwiyanti, Wahdah Norsiah
Tuberculosis is a public health problem that remains a challenge globally
and nationally. Tuberculosis disease caused by the Mycobacterium tuberculosis
bacterium. To diagnose TB disease, laboratory examination using the Molecular
Rapid Test (TCM) can be the most efficient method because this method is more
sensitive and accurate than conventional methods, and at the same time can detect
Rifampicin sensitivity. The purpose of this study was to determine the difference
in the results of TB examination in the TCM method using the GeneXpert tool
against delays in handling sputum toward tuberculosis suspects at Pangeran Jaya
Sumitra Kotabaru Hospital. This research method was Analytical Survey using
the Cross Sectional Studies research design by comparing the results of the
Mycobacterium tuberculosis examination on the sputum sample examined
immediately against sputum sample which was delayed for 12 hours at room
temperature and then the data was analyzed statistically using the Wilcoxon test.
The results showed that from a total of 46 sputum samples observed, the results of
the sputum examination were immediately obtained, namely MTB Not Detected
33 samples, MTB Detected Very Low 3 samples, MTB Detected Low 6 samples,
and MTB Detected Medium 4 samples. For samples that were delayed by 12
hours at room temperature, the results of MTB Not Detected 33 samples, MTB
Detected Very Low 3 samples, MTB Detected Low 6 samples, and MTB Detected
Medium 4 samples were obtained. The conclusion of this study is that there is no
difference in the results of the Mycobacterium tuberculosis test on the sputum
sample immediately with those postponed by 12 hours at room temperature. The
suggestion of this research is that further research is needed regarding other
variables that can affect the results of the TB examination of the TCM method
such as variations in delay of time, temperature, and so on.
Keywords : Mycobacterium tuberculosis, Molecular Rapid Test, Sputum
Detail Information
| Item Type | |
|---|---|
| Penulis |
Yola Febrianti - Personal Name
Dra. Ratih Dewi Dwiyanti, M. Kes - Personal Name Wahdah Norsiah, M.Si - Personal Name Aima Insana, S.Si., M.Si - Personal Name |
| Student ID | |
| Dosen Pembimbing | |
| Penguji | |
| Kode Prodi PDDIKTI | |
| Edisi | |
| Departement | |
| Kontributor | |
| Bahasa |
Indonesia
|
| Penerbit | Jurusan Analis Kesehatan : Banjarbaru., 2022 |
| Edisi | |
| Subyek | |
| No Panggil |
SKP 48AJ 2022
|
| Copyright | |
| Doi |