CD-ROM
GAMBARAN KADAR C-REACTIVE PROTEIN (CRP) PADA PEROKOK AKTIF DI LINGKUNGAN POLTEKKES KEMENKES BANJARMASIN
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ABSTRAK
GAMBARAN KADAR C-REACTIVE PROTEIN (CRP) PADA PEROKOK
AKTIF DI LINGKUNGAN POLTEKKES KEMENKES BANJARMASIN
Peneliti : Syahbrina Nur Anisya
Pembimbing : Wahdah Norsiah, Dinna Rakhmina
Merokok ialah aktivitas membakar tembakau yang kemudian diisap
isinya, baik menggunakan rokok ataupun pipa. Perokok aktif diasumsikan
menderita kerusakan jaringan akibat terpapar oleh racun yang ada pada rokok.
Kerusakan jaringan akan direspon tubuh dengan sekresi C-Reactive Protein
(CRP). CRP merupakan penanda inflamasi dan salah satu protein fase akut yang
disintesis di hati untuk memantau secara non-spesifik penyakit lokal maupun
sistemik. Tujuan penelitian ini untuk mengetahui gambaran kadar CRP pada
perokok aktif berdasarkan lama merokok dan jumlah konsumsi rokok. Jenis
penelitian bersifat survei deskriptif dengan rancangan cross sectional. Sebanyak
30 perokok aktif yang memenuhi kriteria inklusi dan eksklusi diambil darahnya,
kemudian dilakukan pemeriksaan CRP dengan metode aglutinasi lateks. Hasil
penelitian dengan lama merokok 6-10 tahun menunjukkan 89% (normal) dan
11% (abnormal), lama merokok 11-15 tahun 60% (normal) dan 40% (abnormal),
dan lama merokok >20 tahun 86% (normal) dan 14% (abnormal), kemudian
jumlah konsumsi rokok 1-10 batang/hari sebanyak 90% (normal) dan 10%
(abnormal), jumlah konsumsi rokok 11-20 batang/hari sebanyak 82% (normal)
dan 18% (abnormal), dan jumlah konsumsi rokok >20 batang/hari sebanyak 78%
(normal) dan 22% (abnormal). Dari 30 sampel 17% menunjukkan kadar CRP
abnormal dan 83% menunjukkan kadar CRP normal, sehingga dapat
disimpulkan bahwa tidak ada hubungan antara kadar CRP dengan lama merokok
dan jumlah konsumsi rokok. Saran bagi perokok aktif sebaiknya perlahan-lahan
untuk menghentikan kebiasan merokok dan bagi peneliti lain untuk selanjutnya
diperlukan adanya penelitian kadar IL-6 (Interlukin-6) unuk mengukur tingkat
inflamasi pada perokok aktif.
Kata kunci : CRP, perokok aktif, lama merokok, dan jumlah konsumsi rokok
ABSTRACT
DESCRIPTION OF C-REACTIVE PROTEIN (CRP) LEVELS IN ACTIVE
SMOKERS IN THE POLTEKKES KEMENKES BANJARMASIN
Researcher : Syahbrina Nur Anisya
Advisor : Wahdah Norsiah, Dinna Rakhmina
Smoking is the activity of burning tobacco which is then sucked in its
contents, either using cigarettes or pipes. Active smokers are assumed of suffer
tissue damage due to exposure to the toxins present in cigarettes. The body will
respond to tissue damage with the secretion of C-Reactive Protein (CRP). CRP
is an inflammatory marker and one of the acute phase proteins synthesized in the
liver for non-specific monitoring of local and systemic disease. The purpose of
this study was to determine the description of CRP levels in active smokers
based on the length of smoking and the amount of cigarette consumption. This
type of research is a descriptive survey with a cross sectional design. A total of
30 active smokers who met the inclusion and exclusion criteria had their blood
drawn, then CRP examination was performed using the latex agglutination
method. The results of the study with smoking duration of 6-10 years showed
89% (normal) and 11% (abnormal), length of smoking 11-15 years 60%
(normal) and 40% (abnormal), and duration of smoking >20 years 86% (normal)
and 14% (abnormal), then the number of cigarettes consumed 1-10
cigarettes/day was 90% (normal) and 10% (abnormal), the number of cigarettes
consumed 11-20 cigarettes/day was 82% (normal) and 18% (abnormal), and the
number of cigarettes consumption >20 cigarettes/day as much as 78% (normal)
and 22% (abnormal). From 30 samples, 17% showed abnormal CRP levels and
83% showed normal CRP levels, so it can be concluded that there is no
relationship between CRP levels with length of smoking and the number of
cigarette consumption. Suggestion for active smokers should slowly stop
smoking and for other researchers to further study the levels of IL-6 to measure
the level of inflammation in active smokers.
Keyword : CRP, active smoker, long time smoking, and number of cigarette
consumed
Detail Information
| Item Type | |
|---|---|
| Penulis |
Syahbrina Nur Anisya - Personal Name
Wahdah Norsiah, M.Si - Personal Name Dinna Rakhmina, S.Si., M.Sc - Personal Name Tini Elyn Herlina, MM - Personal Name |
| Student ID | |
| Dosen Pembimbing | |
| Penguji | |
| Kode Prodi PDDIKTI | |
| Edisi | |
| Departement | |
| Kontributor | |
| Bahasa |
Indonesia
|
| Penerbit | Jurusan Analis Kesehatan : Banjarbaru., 2022 |
| Edisi | |
| Subyek | |
| No Panggil |
020-KTI-ANK-2022
|
| Copyright | |
| Doi |