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HUBUNGAN KARAKTERISTIK INDIVIDU DENGAN RESPON ANTIBODI ANTI-HBs PASCA VAKSINASI HEPATITIS B PADA PETUGAS KESEHATAN
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ABSTRAK
HUBUNGAN KARAKTERISTIK INDIVIDU DENGAN RESPON ANTIBODI
ANTI-HBs PASCA VAKSINASI HEPATITIS B
PADA PETUGAS KESEHATAN
Peneliti : Norhafizah Mulia Sari
Pembimbing : Wahdah Norsiah, Dinna Rakhmina
Berdasarkan Peraturan Menteri Kesehatan Republik Indonesia Nomor 53 Tahun
2015 petugas kesehatan merupakan kelompok berisiko tinggi terinfeksi Hepatitis B.
Vaksinasi cara paling efektif untuk mengurangi faktor risiko tersebut. Faktor yang
dihubungkan dengan tidak adanya respon imun pasca vaksinasi Hepatitis B yaitu usia
(diatas 40 tahun), pria, obesitas, merokok dan penyakit kronis. Tujuan penelitian ini
untuk mengetahui hubungan karakteristik individu dengan respon antibodi anti-HBs
pasca vaksinasi Hepatitis B pada petugas kesehatan ditinjau dari usia, jenis kelamin,
indeks massa tubuh (IMT), merokok, dan riwayat penyakit. Penelitian ini bersifat
survey analitik dengan rancangan cross-sectional. Populasi penelitian adalah petugas
kesehatan yang sudah vaksinasi Hepatitis B di Puskesmas Kabupaten Banjar dan
sampel diambil dengan teknik purposive sampling sebanyak 30 petugas kesehatan.
Hasil penelitian menunjukkan karakteristik responden usia 17-25 tahun (10%), 26-45
tahun (73%), 46-65 tahun (17%), pria (30%), wanita (70%), non obesitas (50%),
obesitas (50%), tidak merokok (87%), merokok <10 batang/hari (3%), 10-20
batang/hari (10%), tidak ada riwayat penyakit (50%), 1 riwayat penyakit (40%), 2
riwayat penyakit (7%), 3 riwayat penyakit (3%) dan respon antibodi anti-HBs pasca
vaksinasi hepatitis B 19 responden (63%) respon kuat dan 11 responden (37%) respon
lemah. Kesimpulan pada penelitian ini tidak ada hubungan yang signifikan antara
respon antibodi anti-HBs pasca vaksinasi dengan usia, indeks massa tubuh (IMT) dan
riwayat penyakit, sedangkan jenis kelamin dan merokok ada hubungan yang signifikan
dengan respon antibodi anti-HBs pasca vaksinasi. Saran untuk peneliti selanjutnya
untuk mengamati gen yang menyebabkan respon lemah terhadap pembentukan
antibodi pasca vaksinasi.
Kata kunci : vaksinasi, anti-HBs, petugas kesehatan
ABSTRACT
THE CORRELATION OF INDIVIDUAL CHARACTERISTICS WITHAL
ANTI-HBs ANTIBODY RESPONSE AFTER HEPATITIS B
VACCINATION ON HEALTH CARE WORKERS (HCW)
Researcher : Norhafizah Mulia Sari
Supervisor : Wahdah Norsiah, Dinna Rakhmina
Based on the Regulation of the Minister of Health of the Republic of
Indonesia Number 53 of 2015 health workers are a high-risk group for Hepatitis B
infection. Vaccination is the most effective way to reduce these risk factors.
Factors associated with the absence of an immune response after hepatitis B
vaccination were age (over 40 years), male, obesity, smoking, and chronic
disease. The purpose of this study was to determine the correlation between
individual characteristics and anti-HBs antibody response after hepatitis B
vaccination on health workers in terms of age, gender, body mass index (BMI),
smoking status, and disease history. This research is an analytical survey with a
cross-sectional design. The study population was health workers who had been
vaccinated against Hepatitis B at the Banjar District Health Center and samples
were taken using the purposive sampling technique as 30 health workers. The
results showed the characteristics of respondents aged 17-25 years (10%), 26-45
years (73%), 46-65 years (17%), men (30%), women (70%), not obesity (50% ),
obesity (50%), not smoking (87%), smoking 10 cigarettes/day (3%), 10-20
cigarettes/day (10%), no history of disease (50%), 1 history of disease (40 %), 2
medical history (7%), 3 medical history (3%) and the response to anti-HBs
antibodies after Hepatitis B vaccination was 19 people (63%) with a strong
response and 11 people (37%) with a weak response. The Conclusion in this
research that there is no significant correlation between anti-HBs antibody
response after vaccination with age, body mass index (BMI), and disease history,
while of gender and smoking, there was a significant correlation with anti-HBs
antibody response after vaccination. Suggestions for further researchers to observe
genes that cause a weak response to antibody formation after vaccination.
Keywords: vaccination, anti-HBs, health workers
Detail Information
| Item Type | |
|---|---|
| Penulis |
Norhafizah Mulia Sar - Personal Name
Wahdah Norsiah, M.Si - Personal Name Dinna Rakhmina, S.Si,.M.Sc - Personal Name Dra. Anny Thuraidah, Apt.,MS. - Personal Name |
| Student ID | |
| Dosen Pembimbing | |
| Penguji | |
| Kode Prodi PDDIKTI | |
| Edisi | |
| Departement | |
| Kontributor | |
| Bahasa |
Indonesia
|
| Penerbit | Jurusan Analis Kesehatan : Banjarbaru., 2022 |
| Edisi | |
| Subyek | |
| No Panggil |
ANK/ 07 SKP 2022
|
| Copyright | |
| Doi |