Rifqoh Dosen Pembimbing 2 Tini Elyn Herlina Dosen Pembimbing 1 Putri Islamiati Nur Hidayah Pengarang

ABSTRAK Pengaruh Titer Widal Terhadap Jumlah Neutrofil Pada Pasien Suspek Tifoid Peneliti: Putri Islamiati Nur Hidayah Pembimbing: Tini Elyn Herlina ; Rifqoh Menurut data perkiraan terbaru WHO (2018) kasus demam tifoid di dunia, ada 11 hingga 21 juta kasus dan 128.000 hingga 161.000 kematian terkait kejadian demam tifoid setiap tahunnya. Menurut data profil kesehatan Indonesia (2011), kasus demam tifoid di rumah sakit besar di Indonesia ada sebanyak 55.098 kasus demam tifoid. Pada laporan penyakit tifoid Dinas Kesehatan Kota Banjarbaru periode Januari hingga September 2019, kasus demam tifoid sebanyak 1.298 kasus. Demam tifoid terjadi karena adanya infeksi saluran cerna yang disebabkan oleh bakteri Salmonella sp. Dalam penegakkan diagnosis pemeriksaan demam tifoid dilakukan pemeriksaan laboratorium yang meliputi pemeriksaan serologi salah satunya uji widal dan pemeriksaan hematologi yaitu jumlah neutrofil dengan hematology analyzer 5 diff. Penelitian ini dilakukan untuk mengetahui apakah terdapat pengaruh titer widal pada pasien suspek tifoid yang positif dengan titer widal 1/80, 1/160, 1/320, dan 1/640 S.typhi O/H dan S. paratyphi A, B dan C terhadap jumlah neutrofil. Jenis penelitian ini yaitu survey analitik dengan rancangan cross sectional. Populasi penelitian adalah pasien suspek tifoid di RSD Idaman Kota Banjarbaru dengan jumlah 30 sampel periode 13-31 Desember 2019, sampel diambil dengan teknik non probability sampling yaitu accidental sampling. Dari hasil uji statistik titer widal terhadap jumlah neutrofil, terdapat 56,3% pengaruh titer widal terhadap jumlah neutrofil pada pasien suspek tifoid. Dengan persentase pasien yang mengalami penurunan jumlah neutrofil sebanyak 23,33% dan 76,67% tidak mengalami penurunan jumlah neutrofil. Kata kunci : Titer widal, demam tifoid, uji widal, jumlah neutrofil ABSTRACT The Impact of Widal Titer Against Total Neutrophils In Patients Suspected Typhoid Researcher : Putri Islamiati Nur Hidayah Advisor : Tini Elyn Herlina ; Rifqoh According to the latest WHO estimation data (2018) of typhoid fever cases in the world, there are 11 to 21 million cases and 128,000 to 161,000 deaths related to the incidence of typhoid fever each year. According to Indonesian health profile data (2011), there are 55,098 cases of typhoid fever in major hospitals in Indonesia. In the typhoid disease report of Banjarbaru City Health Office for the period of January to September in 2019, there were 1,298 typhoid fever cases. Typhoid fever occurs due to gastrointestinal infections caused by the bacterium Salmonella sp. In establishing the diagnosis of typhoid fever examination a laboratory examination is performed which includes serological examination, one of the examination is widal test also hematological examination, namely the number of neutrophils with a 5 diff hematology analyzer. This research to do to find out the impact of widal titers in patients suspected typhoid with widal titers 1/80, 1/160, 1/320, and 1/640 of S.typhi O / H and S. paratyphi A, B and C to the number of neutrophils. The type of this research is analytic survey with cross sectional design. The population of the research are patient who suspected typhoid fever at Idaman Kota Banjarbaru Hospital with 30 samples on December 13th-31st 2019 with non probality sampling technique was accidental sampling. From the results of the statistical test of widal titer on the number of neutrophils, there are 56,3% impacts of titer widal against total neutrophils in patients suspected typhoid. With the percentage of patients who experienced a decrease in neutrophil counts of 23.33% and 76.67% did not experience a decrease in neutrophil counts. Keywords: widal titer, typhoid fever, widal test, neutrophil count