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<title><![CDATA[EFEKTIVITAS EKSTRAK ETANOL DAUN SENGKUANG  (Dracontomelon dao) SEBAGAI ANTIBAKTERI Propionibacterium acnes]]></title>
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<namePart>Aima Insana</namePart>
<role><roleTerm type="text">Dosen Pembimbing 2</roleTerm></role>
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<namePart>Dra. Ratih Dewi Dwiyanti, M.Kes</namePart>
<role><roleTerm type="text">Dosen Pembimbing 1</roleTerm></role>
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<namePart>Arya Candra Saputra</namePart>
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<publisher><![CDATA[Jurusan Analis Kesehatan ]]></publisher>
<dateIssued><![CDATA[2023]]></dateIssued>
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<note>ABSTRAK 
“Efektivitas Ekstrak Etanol Daun Sengkuang (Dracontomelon dao) 
Sebagai Antibakteri Propionibacterium acnes” 
Peneliti : Arya Candra Saputra 
Pembimbing : Ratih Dewi Dwiyanti, Aima Insana 
Pengobatan jerawat  dapat dilakukan dengan pemberian obat 
antibakteri. Salah satu tumbuhan yang memiliki potensi sebagai obat 
antibakteri yaitu daun sengkuang (Dracontomelon dao) karena adanya 
kandungan senyawa metabolit seperti saponin, alkaloid, flavonoid, steroid 
dan tannin yang berpotensi sebagai antibakteri. Penelitian ini bertujuan 
untuk mengetahui efektivitas ekstrak etanol daun sengkuang 
(Dracontomelon dao) sebagai antibakteri Propionibacterium acnes. Jenis 
penelitian ini adalah eksperimen sungguhan (True experiment) dengan 
rancangan Posttest Only Control Group Design yang terdiri dari 5 
perlakuan ekstrak etanol daun Sengkuang dengan konsentrasi 5%, 15%, 
25%, 35% dan 50% dengan 5 kali pengulangan. Uji aktivitas antibakteri 
dilakukan dengan metode dilusi cair untuk menentukan KHM dan KBM. 
Data dianalisis dengan uji Wilcoxon. Hasil penelitian menunjukkan bahwa 
KHM ekstrak etanol daun sengkuang terhadap pertumbuhan bakteri 
Propionibacterium acnes terjadi pada konsentrasi 5%. Sedangkan KBM 
terjadi pada konsentrasi 15%. Berdasarkan hasil yang diperoleh dapat 
disimpulkan bahwa ekstrak etanol daun sengkuang efektif terhadap 
pertumbuhan bakteri Propionibacterium acnes terjadi pada   konsentrasi 
15%. Saran penelitian ini yaitu perlu penelitian lebih lanjut mengenai 
efektivitas ekstrak etanol daun sengkuang (Dracontomelon dao) dengan 
konsentrasi yang lebih rendah dalam menghambat pertumbuhan bakteri 
Propionibacterium acnes. 
Kata Kunci : Ekstrak, Etanol, Daun Sengkuang (Dracontomelon 
dao), Propionibacterium acnes. 
ix 
ABSTRACT 
“The Effectiveness of Ethanol Extract of Sengkuang Leaves 
(Dracontomelon dao) as an Antibacterial Propionibacterium acnes” 
Researcher : Arya Candra Saputra 
Supervisor : Ratih Dewi Dwiyanti, Aima Insana 
Treatment of acne can be done by giving antibacterial drugs. One of 
the plants that has the potential as an antibacterial drug is sengkuang leaf 
(Dracontomelon dao) due to the presence of metabolite compounds such 
as saponins, alkaloids, flavonoids, steroids and tannins which have 
potential as antibacterials. This study aims to determine the effectiveness 
of the ethanol extract of sengkuang leaves (Dracontomelon dao) as an 
antibacterial for Propionibacterium acnes. This type of research is a real 
experiment (True experiment) with a Posttest Only Control Group Design 
consisting of 5 treatments of Sengkuang leaf ethanol extract with 
concentrations of 5%, 15%, 25%, 35% and 50% with 5 repetitions. The 
antibacterial activity test was carried out using the MIC and MBC liquid 
dilution method. The data were analyzed with Wilcoxon test. The results 
showed that the MIC of the ethanol extract of sengkuang leaves on the 
growth of Propionibacterium acnes bacteria occurred at a concentration of 
10%. Meanwhile, MBC occurs at a concentration of 15%. Based on the 
results obtained, it can be concluded that the ethanol extract of sengkuang 
leaves is effective against the growth of Propionibacterium acnes bacteria 
occurring at a concentration of 15%. The suggestion of this research is that 
further research is needed regarding the effectiveness of the ethanol extract 
of sengkuang leaves (Dracontomelon dao) at a lower concentration in 
inhibiting the growth of Propionibacterium acnes bacteria. 
Key Word : Extract, Ethanol, Sengkuang Leaf (Dracontomelon dao), 
Propionibacteriumacnes</note>
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